How Long After BOTOX® Can You Work Out? What To Know Before Hitting the Gym Posted on November 21, 2025 By Dr. Edward Gross In most cases, it's best to avoid strenuous workouts for at least 24 hours—and sometimes up to 48 hours—after BOTOX injections. While BOTOX requires virtually no downtime, exercising too soon after treatment can affect how well it works. If you're wondering how long after BOTOX you can work out, the short answer is: Wait at … Read More